Clinical researchAnimal modelsReviews


Clinical research

TitleThe Impact of Age and Body Composition on the Agreement between Estimated and Measured GFR in Heart Transplant Recipients.
AuthorsHornum M, Jørgensen MB, Sidenius Nelson LM, Feldt-Rasmussen B, Rossing K, Porrini E, Oturai P, Gustafsson F.
Year2025
JournalNephron Nephron. 2025;149(1):18-28.
DOI10.1159/000540530
TitleMeasured glomerular filtration rate predicts liver related deaths better than estimated glomerular filtration rate in advanced chronic liver disease.
AuthorsGonzález-Alayón C, Hernández-Guerra M, Luis-Lima S, Cruz Perera Lima C, Santana-Delgado A, Díaz-Mesa C, Morant-Domínguez A, Martín LD, González-Rinne F, Hernández-Bustabad A, Moreno M, Gaspari F, Porrini E.
Year2025
JournalDigestive and Liver Disease Dig Liver Dis. 2025 Feb;57(2):477-484.
DOI10.1016/j.dld.2024.09.016
TitleRenal functional reserve in living kidney donors.
AuthorsGonzález Rinne A, Acosta Sorensen C, Reseghetti E, Rivero Viera Y, Stefany Rincón M, Martín Izquierdo E, Alonso Bethencourt A, Morales A, Cabello Moya E, González S, González Cabrera F, Fariña Hernández A, Luis-Lima S, Díaz Martín L, Escamilla B, Cruz C, González Rinne F, Pérez Tamajón L, Gaspari F, Hernández Marrero D, Porrini E.
Year2025
JournalClinical Kidney Journal Clin Kidney J. 2025 Feb 22;18(4):sfaf053.
DOI10.1093/ckj/sfaf053
TitleComparative performance of CKD-EPI equations in people with diabetes: An international pooled analysis of individual participant data.
AuthorsKwok R, Kishore K, Zafari T, Koye DN, Hachem M, de Boer IH, Jeong TD, Min WK, Porrini E, Bjornstad P, MacIsaac RJ, Churilov L, Ekinci EI.
Year2025
JournalDiabetes Research and Clinical Practice Diabetes Res Clin Pract. 2025 May;223:112104.
DOI10.1016/j.diabres.2025.112104
TitleMeasurement, Estimation, and Correlates of the Glomerular Filtration Rate before and after Bariatric Surgery.
AuthorsFriedman AN, Chang AR, Chuah LL, Favre GA, Grangeon-Chapon C, Lane K, Li Y, le Roux CW, Lieske JC, Morales E, Porrini E, Chagnac A.
Year2025
JournalJournal of the American Society of Nephrology J Am Soc Nephrol. 2025 Jul 15.
DOI10.1681/ASN.0000000797
TitleDetection of binucleated nephrin-marked podocytes by flow cytometry in the urine of patients with obesity.
AuthorsCarrasco AG, Izquierdo-Lahuerta A, de Pablos IG, Vila-Bedmar R, Martin-Taboada M, Porrini E, Morales E, Medina-Gómez G.
Year2024
JournalJournal of Nephrology J Nephrol. 2024 Jan;37(1):245-248.
DOI10.1007/s40620-023-01730-9
TitleThe error of estimated GFR in predialysis care.
AuthorsEscamilla-Cabrera B, Luis-Lima S, Gallego-Valcarce E, Sánchez-Dorta NV, Negrín-Mena N, Díaz-Martín L, Cruz-Perera C, Hernández-Valles AM, González-Rinne F, Rodríguez-Gamboa MJ, Estupiñán-Torres S, Miquel-Rodríguez R, Cobo-Caso MÁ, Delgado-Mallén P, Fernández-Suárez G, González-Rinne A, Hernández-Barroso G, González-Delgado A, Torres-Ramírez A, Jiménez-Sosa A, Ortiz A, Gaspari F, Hernández-Marrero D, Porrini EL.
Year2024
JournalScientific Reports Sci Rep. 2024 Mar 3;14(1):5219.
DOI10.1038/s41598-024-55022-8
TitleMeasured and Estimated Glomerular Filtration Rate to Evaluate Rapid Progression and Changes over Time in Autosomal Polycystic Kidney Disease: Potential Impact on Therapeutic Decision-Making.
AuthorsMiquel-Rodríguez R, González-Toledo B, Pérez-Gómez MV, Cobo-Caso MÁ, Delgado-Mallén P, Estupiñán S, Cruz-Perera C, Díaz-Martín L, González-Rinne F, González-Delgado A, Torres A, Gaspari F, Hernández-Marrero D, Ortiz A, Porrini E, Luis-Lima S.
Year2024
JournalInternational Journal of Molecular Sciences Int J Mol Sci. 2024 May 5;25(9):5036.
DOI10.3390/ijms25095036
TitleImpact and consequences of the error of estimated GFR in patients with heart failure.
AuthorsJorge-Pérez P, García-González MJ, Martín-Cabeza MM, Negrín-Mena N, Luis-Lima S, González-Rinne F, Bosa-Ojeda F, Gaspari F, Díaz Martín L, Porrini E.
Year2024
JournalScientific Reports Sci Rep. 2024 Oct 28;14(1):25840.
DOI10.1038/s41598-024-71425-z
TitleEfficacy of the Once-Daily Tacrolimus Formulation LCPT Compared to the Immediate-Release Formulation in Preventing Early Post-Transplant Diabetes in High-Risk Kidney Transplant Patients: A Randomized, Controlled, Open-Label Pilot Study (EUDRACT: 2017-000718-52).
AuthorsTorres A, Rodríguez-Adanero C, Fernández-Rivera C, Marrero-Miranda D, de Bonis-Redondo E, Rodríguez-Hernández AP, Pérez-Tamajón L, González-Rinne A, Álvarez-Sosa D, Álvarez-González A, Sanchez-Dorta N, Pérez-Carreño E, Díaz-Martín L, Luis-Lima S, Rodríguez-Rodríguez AE, Vera González AM, Romero-Delgado C, Calvo-Rodríguez M, Seijo-Bestilleiro R, Rodríguez-Jiménez C, Prieto López MA, Rivero-González AM, Hernández-Marrero D, Porrini E.
Year2024
JournalJournal of Clinical Medicine J Clin Med. 2024 Dec 20;13(24):7802.
DOI10.3390/jcm13247802
TitleInflammation on the Waiting List Is a Risk Factor for New-Onset Prediabetes and Post-Transplant Diabetes Mellitus: A Prospective Study
AuthorsGonzález Delgado A, Hernández AF, Marrero D, Maside AF, Barroso GH, Carreño EP, Acosta Sørensen C, Rodríguez-Rodríguez AE, Collantes T, Anabel R, Álvarez CR, Rivero A, Jiménez Sosa A, Macia M, Terán García E, Álvarez González A, González Rinne A, Rodríguez A, Redondo EB, Rodríguez Adanero C, Hernández D, Torres Ramírez A, Porrini E
Year2023
JournalNephron Nephron. 2023;147(9):560-571
DOI10.1159/000531334
TitlePretransplant evaluation and the risk of glucose metabolic alterations after renal transplantation: a prospective study.
AuthorsFariña-Hernández A, Marrero-Miranda D, Perez-Carreño E, De Vera-Gonzalez A, González A, Acosta-Sorensen C, Rodríguez-Rodríguez AE, Collantes T, García MDP, Rodríguez-Muñoz AI, Rodriguez-Alvarez C, Rivero A, Macía M, Teran E, Sanchez-Dorta NV, Perez-Tamajón L, Alvarez-González A, González-Rinne A, Rodríguez-Hernández A, De Bonis-Redondo E, Rodriguez-Adanero C, Hernández D, Porrini E, Torres A.
Year2023
JournalNephrology Dialysis Transplantation Nephrol Dial Transplant. 2023 Feb 28;38(3):778-786.
DOI10.1093/ndt/gfac256
TitlePost-transplant diabetes mellitus and renal cell cancer after renal transplantation
AuthorsPorrini E, Montero N, Díaz JM, Lauzurrica R, Rodríguez JO, Torres IS, Moreso F, Cruzado JM, Ruiz RB, Vilaró MI, Lima MXM, Ramchand SK, Ruiz JC, Gainza de Los Rios F, Alvarez CR, Guindo MDCG, Macías M, Vela DB, Osuna A, Bayés-Genís B, Sanchez CA, Ruiz MDC, Rodríguez AER, Rollán RD, Rinne FG, Sosa AJ, Mallén PD, Rinne AG, Miranda DM, Torres A
Year2023
JournalNephrology Dialysis Transplantation Nephrol Dial Transplant. 2023 May 31;38(6):1552-1559
DOI10.1093/ndt/gfac291
TitleExercise and Prediabetes After Renal Transplantation (EXPRED-I): A Prospective Study
AuthorsMorales Febles R, Marrero Miranda D, Jiménez Sosa A, González Rinne A, Cruz Perera C, Rodríguez-Rodríguez AE, Álvarez González A, Díaz Martín L, Negrín Mena N, Acosta Sørensen C, Pérez Tamajón L, Rodríguez Hernández A, González Rinne F, Dorta González A, Ledesma Pérez E, González Delgado A, Domínguez-Rodríguez A, García Baute MDC, Torres Ramírez A, Porrini E
Year2023
JournalSports Medicine – Open Sports Med Open. 2023 May 18;9(1):32
DOI10.1186/s40798-023-00574-8
TitleTherapeutic exercise on metabolic and renal outcomes in patients with Chronic Kidney Disease (CKD): A narrative review
AuthorsMorales Febles R, Marrero Miranda D, Cruz Perera CC, Díaz Martín L, Rodríguez-Rodríguez AE, González Martín AR, Sánchez Báez DJ, Porrini E
Year2023
JournalNephron Nephron. 2023 Aug 23
DOI10.1159/000531921
TitleDecaying kidney function during cirrhosis correlates with remodeling of distal colon aldosterone target gene expression
AuthorsSerrano-Morillas N, González-Alayón C, Vastola-Mascolo A, Rodríguez-Rodríguez AE, Hernández G, Porrini E, Hernández-Guerra M, Alvarez de la Rosa D
Year2023
JournalAmerican Journal of Physiology-Gastrointestinal and Liver Physiology Am J Physiol Gastrointest Liver Physiol. 2023 Oct 1;325(4):G306-G317
DOI10.1152/ajpgi.00073.2023
TitleDrastic decline in vasoactive intestinal peptide expression in the suprachiasmatic nucleus in obese mice on a long-term high-fat diet
AuthorsAfonso-Oramas D, Santana-Cordón L, Lemus-Mesa A, Teixidó-Trujillo S, Rodríguez-Rodríguez AE, Cruz-Muros I, González-Gómez M, Barroso-Chinea P
Year2023
JournalBrain Research Bulletin Brain Res Bull. 2023 Oct 1;202:110756
DOI10.1016/j.brainresbull.2023.110756
TitleEarly glomerular filtration rate changes in living kidney donors and recipients: an example of renal plasticity
AuthorsRinne AG, Sorensen CA, Lima SL, Gil MG, Mena NN, Martín LD, Ramírez A, Morales A, Vega N, Gallego E, Izquierdo EM, Cabello E, Rodríguez AER, González JP, Escamilla B, Cruz C, Tamajón LP, Ramírez AT, Gaspari F, Ortiz A, Porrini E
Year2022
JournalClinical Kidney Journal Clin Kidney J. 2022 Jan 31;15(5):885-894
DOI10.1093/ckj/sfab220
TitleEstimating Renal Function Following Lung Transplantation
AuthorsHornum M, Houlind MB, Iversen E, Porrini E, Luis-Lima S, Oturai P, Iversen M, Bredahl P, Carlsen J, Møller CH, Andersen MJ, Feldt-Rasmussen B, Perch M
Year2022
JournalJournal of Clinical Medicine J Clin Med. 2022 Mar 9;11(6):1496
DOI10.3390/jcm11061496
TitleEstimated glomerular filtration rate by formulas in patients with cirrhosis: An unreliable procedure
AuthorsGonzález-Alayón C, Porrini E, Luis-Lima S, Negrín-Mena N, Moreno M, Morales-Arráez D, González-Rinne F, Díaz-Martín L, Gaspari F, González-Delgado A, Ferrer-Moure C, Ortiz-Arduán A, Hernandez-Guerra M
Year2022
JournalLiver International Liver Int. 2022 Apr;42(4):884-895
DOI10.1111/liv.15134
TitleEstimated GFR in autosomal dominant polycystic kidney disease: errors of an unpredictable method
AuthorsRodríguez RM, Luis-Lima S, Fernandez JM, Gómez MVP, Toledo BG, Cobo M, Delgado-Mallén P, Escamilla B, Marco CO, Estupiñán S, Perera CC, Mena NN, Martín LD, Reyes SP, González IH, González-Rinne F, González-Delgado A, Ferrer-Moure C, Zulueta BL, Torres A, Rodriguez Pérez JC, Gaspari F, Ortiz A, Porrini E
Year2022
JournalJournal of Nephrology J Nephrol. 2022 Nov;35(8):2109-2118
DOI10.1007/s40620-022-01286-0
TitleEvaluation of commercially available glucagon receptor antibodies and glucagon receptor expression.
AuthorsBomholt AB, Johansen CD, Christensen JB, Kjeldsen SAS, Galsgaard KD, Winther-Sørensen M, Serizawa R, Hornum M, Porrini E, Pedersen J, Ørskov C, Gluud LL, Sørensen CM, Holst JJ, Albrechtsen R, Wewer Albrechtsen NJ.
Year2022
JournalCommunications Biology Commun Biol. 2022 Nov 22;5(1):1278.
DOI10.1038/s42003-022-04242-7
TitleRenoprotective role of bariatric surgery in patients with established chronic kidney disease
AuthorsMorales E, Porrini E, Martin-Taboada M, Luis-Lima S, Vila-Bedmar R, González de Pablos I, Gómez P, Rodríguez E, Torres L, Lanzón B, Rodríguez AE, Maíz M, Medina-Gómez G, Praga M
Year2021
JournalClinical Kidney Journal Clin Kidney J. 2020 Dec 23;14(9):2037-2046
DOI10.1093/ckj/sfaa266
TitleRenal histology across the stages of chronic kidney disease
AuthorsTrevisani F, Di Marco F, Capitanio U, Dell’Antonio G, Cinque A, Larcher A, Lucianò R, Bettiga A, Vago R, Briganti A, Salonia A, Montorsi F, Porrini E
Year2021
JournalJournal of Nephrology J Nephrol 2021 Jan 4
DOI10.1007/s40620-020-00905-y
TitleEstimated GFR Slope in Kidney Transplant Patients: When the Error Is Random
AuthorsSergio Luis-Lima, Domingo Marrero-Miranda, Ana González-Rinne, Natalia Negrín-Mena, Lourdes Pérez-Tamajón, Aurelio Rodríguez, Alejandra Alvarez-González, Alejandra González-Delgado, Carmen Ferrer-Moure, Federico González-Rinne, Laura Díaz Martín, Ana Elena Rodríguez-Rodríguez, Laura Gómez-Díaz, Verónica García-Cabrera, Alejandro Jiménez-Sosa, Armando Torres, Alberto Ortiz, Flavio Gaspari, Esteban Porrini
Year2021
JournalTransplantation Transplantation: February 23, 2021 – Volume Online First – Issue
DOI10.1097/TP.0000000000003719
TitlePost-Transplant Diabetes Mellitus and Prediabetes in Renal Transplant Recipients: An Update
AuthorsRodríguez-Rodríguez A.E; Porrini E.; Hornum M; Donate-Correa J; Morales-Febles R; Khemlani Ramchand S; Molina Lima M.X.; Torres A
Year2021
JournalNephron 2021 Apr 26;1-13
DOI10.1159/000514288
TitleThe Role of Vascular Lesions in Diabetes Across a Spectrum of Clinical Kidney Disease
AuthorsRodríguez-Rodríguez R, Hojs R, Trevisani F, Morales E, Fernández G, Bevc S, Cases Corona CM, Cruzado JM, Quero M, Navarro Díaz M, Bettiga A, Di Marco F, López Martínez M, Moreso F, García Garro C, Khazim K, Ghanem F, Praga M, Ibernón M, Laranjinha I, Mendonça L, Bigotte Vieira M, Hornum M, Feldt-Rasmussen B, Fernández-Fernández B, Concepción PF, Negrín Mena N, Ortiz A, Porrini E; DIABESITY working group of the ERA
Year2021
JournalKidney International Kidney Int Rep. 2021 Jun 12;6(9):2392-2403
DOI10.1016/j.ekir.2021.06.001
TitleAthlete Heart in Children and Young Athletes. Echocardiographic Findings in 331 Cases
AuthorsRodriguez-López AM, Javier González-Pérez, Carmen P, Esteban Porrini, Luisa GC, Tomas F, Josefa HM, Luis F
Year2021
JournalPediatric Cardiology Pediatr Cardiol. 2022 Feb;43(2):407-412
DOI10.1007/s00246-021-02736-5
TitleRenal Function Assessment Gap in Clinical Practice: An Awkward Truth
AuthorsTrevisani F, Di Marco F, Capitanio U, Larcher A, Bettiga A, Dosio F, Ghidini M, Del Conte G, Vago R, Cinque A, Gianolli L, Salonia A, Briganti A, Luis-Lima S, Negrín-Mena N, Montorsi F, Porrini E
Year2020
JournalKidney and Blood Pressure Research Kidney Blood Press Res. 2020;45(2):166-179
DOI10.1159/000504649
TitleA Simplified Iohexol-Based Method to Measure Renal Function in Sheep Models of Renal Disease
AuthorsLuis-Lima S, Mas-Sanmartin C, Rodríguez-Rodríguez AE, Porrini E, Ortiz A, Gaspari F, Diaz-Martin L, Åsberg A, Jenssen T, Jiménez-Sosa A, Martinez-Ros P, Gonzalez-Bulnes A
Year2020
JournalBilogy (on MDPI) Biology (Basel). 2020 Aug 31;9(9):259
DOI10.3390/biology9090259
TitleExercise and Prediabetes after Renal Transplantation (EXPRED): Protocol Description
AuthorsMorales Febles R, Negrín Mena N, Rodríguez-Rodríguez AE, Díaz Martín L, González Rinne F, Marrero Miranda D, González Rinne A, Álvarez González A, Pérez Tamajón L, Acosta Sørensen C, Rodríguez Hernández A, Domínguez-Rodríguez A, García Baute MDC, Torres Ramírez A, Porrini E
Year2020
JournalNephron Nephron. 2021;145(1):55-62
DOI10.1159/000511320
TitleResponse to “Iohexol-measured glomerular filtration rate in children and adolescents with chronic kidney disease: a pilot study comparing venous and finger stick methods”
AuthorsLuis-Lima S, Gaspari F, Carrara F, Porrini E
Year2019
JournalPediatric Nephrology volume 34, pages1629?1630(2019)
DOI10.1007/s00467-019-04285-9
TitleCKD staging with cystatin C or creatinine-based formulas: flipping the coin
AuthorsLuis-Lima S, Escamilla-Cabrera B, Negrín-Mena N, Estupiñán S, Delgado-Mallén P, Marrero-Miranda D, González-Rinne A, Miquel-Rodríguez R, Cobo-Caso MÁ, Hernández-Guerra M, Oramas J, Batista N, Aldea-Perona A, Jorge-Pérez P, González-Alayón C, Moreno-Sanfiel M, González-Rodríguez JA, Henríquez L, Alonso-Pescoso R, Díaz-Martín L, González-Rinne F, Lavín-Gómez BA, Galindo-Hernández J, Sánchez-Gallego M, González-Delgado A, Jiménez-Sosa A, Torres A, Porrini E
Year2019
JournalNephrology Dialysis Transplantation Volume 34, Issue 2, February 2019, Pages 287?294
DOI10.1093/ndt/gfy086
TitleImpact of errors of creatinine and cystatin C equations in the selection of living kidney donors
AuthorsGonzález-Rinne A, Luis-Lima S, Escamilla B, Negrín-Mena N, Ramírez A, Morales A, Vega N, García P, Cabello E, Marrero-Miranda D, Aldea-Perona A, Alvarez A, Abad MDC, Pérez-Tamajón L, González-Rinne F, González-Delgado A, Díaz Martín L, Jiménez-Sosa A, Torres A, Porrini E
Year2019
JournalClinical Kidney Journal Clin Kidney J. 2019 Mar 18;12(5):748-755
DOI10.1093/ckj/sfz012
TitleThe Error of Estimated GFR in Type 2 Diabetes Mellitus
AuthorsLuis-Lima S, Higueras Linares T, Henríquez-Gómez L, Alonso-Pescoso R, Jimenez A, López-Hijazo AM, Negrín-Mena N, Martín C, Sánchez-Gallego M, Galindo-Hernández SJ, Socas Fernández Del Castillo R, Castilla-Marrero M, Domínguez-Coello S, Vilchez de León V, Valcárcel-Lopez R, Insausti-Garmendia N, Escamilla B, Estupiñán S, Delgado-Mallén P, Armas-Padrón AM, Marrero-Miranda D, González-Rinne A, Miquel Rodríguez RM, Cobo-Caso MA, Díaz-Martín L, González-Rinne F, González-Delgado A, López-Martínez M, Jiménez-Sosa A, Torres A, Porrini E
Year2019
JournalJournal of Clinical Medicine J Clin Med. 2019 Sep 26;8(10). pii: E1543
DOI10.3390/jcm8101543
TitleThe estimation of GFR and the adjustment for BSA in overweight and obesity: a dreadful combination of two errors
AuthorsLópez-Martínez M, Luis-Lima S, Morales E, Navarro-Díaz M, Negrín-Mena N, Folgueras T, Escamilla B, Estupiñán S, Delgado-Mallén P, Marrero-Miranda D, González-Rinne A, Miquel-Rodríguez RM, Cobo-Caso MA, Díaz-Martín L, Jiménez-Sosa A, González-Rinne F, Torres A, Porrini E
Year2019
JournalInternational Journal of Obesity Int J Obes (Lond). 2019 Oct 22
DOI10.1038/s41366-019-0476-z
TitleMeasured GFR by Utilizing Population Pharmacokinetic Methods to Determine Iohexol Clearance
AuthorsÅsberg A, Bjerre A, Almaas R, Luis-Lima S, Robertsen I, Salvador CL, Porrini E, Schwartz GJ, Hartmann A, Bergan S
Year2019
JournalKidney International Reports Kidney Int Rep. 2019 Dec 6;5(2):189-198
DOI10.1016/j.ekir.2019.11.012
TitlePrediabetes is a risk factor for cardiovascular disease following renal transplantation.
AuthorsPorrini E, Díaz JM, Moreso F, Lauzurrica R, Ibernon M, Torres IS, Ruiz RB, Rodríguez Rodríguez AE, Mallén PD, Bayés-Genís B, Gainza FJ, Osorio JM, Osuna A, Domínguez R, Ruiz JC, Sosa AJ, Rinne AG, Miranda DM, Macías M, Torres A.
Year2019
JournalKidney International Kidney Int. 2019 Dec;96(6):1374-1380.
DOI10.1016/j.kint.2019.06.026
TitleIohexol plasma clearance simplified by dried blood spot testing
AuthorsSergio Luis-Lima, Flavio Gaspari, Natalia Negrín-Mena, Fabiola Carrara, Laura Díaz-Martín, Alejandro Jiménez-Sosa, Federico González-Rinne, Armando Torres, Esteban Porrini
Year2018
JournalNephrology Dialysis Transplantation Volume 33, Issue 9, September 2018, Pages 1597?1603
DOI10.1093/ndt/gfx323
TitleEstimated Glomerular Filtration Rate in Renal Transplantation: The Nephrologist in the Mist
AuthorsLuis-Lima S, Marrero-Miranda D, González-Rinne A, Torres A, González-Posada JM, Rodríguez A, Salido E, Aldea-Perona A, Gaspari F, Carrara F, Gómez-Gerique JA, Negrín-Mena N, Pérez-Tamajón L, González-Rinne F, Jiménez-Hernández H, Jiménez-Sosa A, Porrini E
Year2015
JournalTransplantation 2015 Dec;99(12):2625-33
DOI10.1097/TP.0000000000000786
TitleMeasurement of glomerular filtration rate: internal and external validations of the iohexol plasma clearance technique by HPLC
AuthorsLuis-Lima S, Gaspari F, Porrini E, García-González M, Batista N, Bosa-Ojeda F, Oramas J, Carrara F, González-Posada JM, Marrero D, Salido E, Torres A, Jiménez-Sosa A
Year2014
JournalClinica Chimica Acta Clin Chim Acta. 2014 Mar 20;430:84-5
DOI10.1016/j.cca.2013.12.028
TitleThe GFR and GFR decline cannot be accurately estimated in type 2 diabetics
AuthorsGaspari F, Ruggenenti P, Porrini E, Motterlini N, Cannata A, Carrara F, Jiménez Sosa A, Cella C, Ferrari S, Stucchi N, Parvanova A, Iliev I, Trevisan R, Bossi A, Zaletel J, Remuzzi G
Year2013
JournalKidney International July 2013 Volume 84, Issue 1, Pages 164?173
DOI10.1038/ki.2013.47
TitleMeasurable Urinary Albumin Predicts Cardiovascular Risk among Normoalbuminuric Patients with Type 2 Diabetes
AuthorsRuggenenti P, Porrini E, Motterlini N, Perna A, Ilieva AP, Iliev IP, Dodesini AR, Trevisan R, Bossi A, Sampietro G, Capitoni E, Gaspari F, Rubis N, Ene-Iordache B, Remuzzi G
Year2012
JournalJournal of the American Society of Nephrology J Am Soc Nephrol. 2012 Oct;23(10):1717-24
DOI10.1681/ASN.2012030252
TitleGlomerular hyperfiltration and renal disease progression in type 2 diabetes
AuthorsRuggenenti P, Porrini EL, Gaspari F, Motterlini N, Cannata A, Carrara F, Cella C, Ferrari S, Stucchi N, Parvanova A, Iliev I, Dodesini AR, Trevisan R, Bossi A, Zaletel J, Remuzzi G
Year2012
JournalDiabetes Care 2012 Oct; 35(10): 2061-2068
DOI10.2337/dc11-2189
TitleHyperinsulinemia and hyperfiltration in renal transplantation
AuthorsPorrini E, Bayes B, Diaz JM, Ibernon M, Benitez R, Domínguez R, Moreno JM, Delgado P, Lauzurica R, Silva I, Moreso F, Lampreabe I, Arias M, Osuna A, Torres A
Year2009
JournalTransplantation 2009, 27;87:274-9
DOI10.1097/TP.0b013e318191a7d5


Animal models

TitleRole of obesity and estrogen deficiency in non-alcoholic fatty liver disease: Insights from a mouse model.
AuthorsAfonso-Alí A, Dicroce-Giacobini J, Teixido-Trujillo S, Porrini E, Pérez-Pérez JA, García-Hernández S, Luis-Lima S, Abrante-Pérez B, Hernández-Bustabad A, Acosta-González NG, Iglesias-Hernández M, Díaz-Martín L, Rodríguez-González C, Hernández-Guerra M, Rodríguez-Rodríguez AE.
Year2025
JournalMolecular Medicine Reports Mol Med Rep. 2025 Oct;32(4):264.
DOI10.3892/mmr.2025.13629
TitleInduction of diabetes by Tacrolimus in a phenotypic model of obesity and metabolic syndrome.
AuthorsTeixidó-Trujillo S, Porrini E, Menéndez-Quintanal LM, Torres-Ramírez A, Fumero C, Rodríguez-Rodríguez AE.
Year2024
JournalFrontiers in Endocrinology Front Endocrinol (Lausanne). 2024 Apr 29;15:1388361.
DOI10.3389/fendo.2024.1388361
TitleIntegrated miRNA-mRNA Analysis Reveals Critical miRNAs and Targets in Diet-Induced Obesity-Related Glomerulopathy.
AuthorsLópez-Martínez M, Armengol MP, Pey I, Farré X, Rodríguez-Martínez P, Ferrer M, Porrini E, Luis-Lima S, Díaz-Martín L, Rodríguez-Rodríguez AE, Cruz-Perera C, Alcalde M, Navarro-Díaz M.
Year2024
JournalInternational Journal of Molecular Sciences Int J Mol Sci. 2024 Jun 11;25(12):6437.
DOI10.3390/ijms25126437
TitleThe Role of Gender Differences and Menopause in Obesity-Related Renal Disease, Renal Inflammation and Lipotoxicity
AuthorsAfonso-Alí A, Porrini E, Teixido-Trujillo S, Pérez-Pérez JA, Luis-Lima S, Acosta-González NG, Sosa-Paz I, Díaz-Martín L, Rodríguez-González C, Rodríguez-Rodríguez AE
Year2023
JournalInternational Journal of Molecular Sciences Int J Mol Sci. 2023 Aug 19;24(16):12984
DOI10.3390/ijms241612984
TitleMeasured GFR in murine animal models: review on methods, techniques, and procedures
AuthorsTeixido-Trujillo S, Luis-Lima S, López-Martínez M, Navarro-Díaz M, Díaz-Martín L, Escasany-Martínez E, Gaspari F, Rodríguez-Rodríguez AE
Year2023
JournalPflügers Archiv – European Journal of Physiology Pflugers Arch. 2023 Nov;475(11):1241-1250
DOI10.1007/s00424-023-02841-9
TitleA High-Fat Diet Modifies Brain Neurotransmitter Profile and Hippocampal Proteome and Morphology in an IUGR Pig Model.
AuthorsYeste N, Pérez-Valle J, Heras-Molina A, Pesántez-Pacheco JL, Porrini E, González-Bulnes A, Bassols A.
Year2022
JournalNutrients Nutrients. 2022 Aug 22;14(16):3440.
DOI10.3390/nu14163440
TitleObesity and Metabolic Traits after High-Fat Diet in Iberian Pigs with Low Birth Weight of Placental Origin.
AuthorsHeras-Molina A, Yeste N, Pesantez-Pacheco JL, Astiz S, Vazquez-Gomez M, Bettiga A, Trevisani F, Garcia-Contreras C, Luis-Lima S, Bassols A, Porrini E, Gonzalez-Bulnes A.
Year2022
JournalBilogy (on MDPI) Biology (Basel). 2022 Oct 19;11(10):1533.
DOI10.3390/biology11101533
TitleIohexol plasma clearance simplified by Dried Blood Spot (DBS) sampling to measure renal function in conscious mice
AuthorsAna Elena Rodríguez-Rodríguez, Sergio Luis-Lima, Javier Donate-Correa, Laura Diaz-Martín, María Rosa Arnau, Alejandro Jiménez-Sosa, Flavio Gaspari, Alberto Ortiz, Esteban Porrini
Year2021
JournalScientific Reports Sci Rep 11, 4591 (2021)
DOI10.1038/s41598-021-83934-2
TitleObesity and metabolic syndrome induce hyperfiltration, glomerulomegaly, and albuminuria in obese ovariectomized female mice and obese male mice
AuthorsRodríguez-Rodríguez AE, Donate-Correa J, Luis-Lima S, Díaz-Martín L, Rodríguez-González C, Pérez-Pérez JA, Acosta-González NG, Fumero C, Navarro-Díaz M, López-Álvarez D, Villacampa-Jiménez J, Navarro-González JA, Ortiz A, Porrini E
Year2021
JournalMenopause Menopause. 2021 Sep 27;28(11):1296-1306
DOI10.1097/GME.0000000000001842
TitleThe Iberian pig fed with high-fat diet: a model of renal disease in obesity and metabolic syndrome
AuthorsRodríguez RR, González-Bulnes A, Garcia-Contreras C, Elena Rodriguez-Rodriguez A, Astiz S, Vazquez-Gomez M, Luis Pesantez J, Isabel B, Salido-Ruiz E, González J, Donate Correa J, Luis-Lima S, Porrini E
Year2019
JournalInternational Journal of Obesity 2019 Oct 21
DOI10.1038/s41366-019-0434-9
TitleInhibition of the mTOR pathway: A new mechanism of ß cell toxicity induced by tacrolimus.
AuthorsRodriguez-Rodriguez AE, Donate-Correa J, Rovira J, Cuesto G, Luis-Ravelo D, Fernandes MX, Acevedo-Arozena A, Diekmann F, Acebes A, Torres A, Porrini E.
Year2019
JournalAmerican Journal of Transplantation Am J Transplant. 2019 Dec;19(12):3240-3249.
DOI10.1111/ajt.15483
TitleA Simple Method to Measure Renal Function in Swine by the Plasma Clearance of Iohexol
AuthorsLuis-Lima S, García-Contreras C, Vázquez-Gómez M, Astiz S, Carrara F, Gaspari F, Negrín-Mena N, Jiménez-Sosa A, Jiménez-Hernández H, González-Bulnes A, Porrini E
Year2018
JournalInternational Journal of Molecular Sciences Int J Mol Sci. 2018 Jan 12;19(1). pii: E232
DOI10.3390/ijms19010232
TitleCharacterization of Ageing- and Diet-Related Swine Models of Sarcopenia and Sarcopenic Obesity
AuthorsGarcia-Contreras C, Vazquez-Gomez M, Torres-Rovira L, Gonzalez J, Porrini E, Gonzalez-Colaço M, Isabel B, Astiz S, Gonzalez-Bulnes A
Year2018
JournalInternational Journal of Molecular Sciences Int. J. Mol. Sci. 2018, 19(3), 823
DOI10.3390/ijms19030823
TitleSimplified Method to Measure Glomerular Filtration Rate by Iohexol Plasma Clearance in Conscious Rats
AuthorsCarrara F, Azzollini N, Nattino G, Corna D, Villa S, Cerullo D, Zoja C, Abrante B, Luis-Lima S, Porrini E, Cannata A, Ferrari S, Fois M, Stucchi N and Gaspari F
Year2016
JournalNephron 2016;133:62-70
DOI10.1159/000445843
TitleIohexol plasma clearance, a simple and reliable method to measure renal function in conscious mice
AuthorsLuis-Lima S, Rodríguez-Rodríguez AE, Martín-Higueras C, Sierra-Ramos C, Carrara F, Arnau MR, de la Rosa DA, Salido E, Gaspari F, Porrini E
Year2016
JournalPflügers Archiv – European Journal of Physiology Pflugers Arch – Eur J Physiol (2016) 468: 1587
DOI10.1007/s00424-016-1843-4


Reviews

TitleSEN, SLANH, and SEEDO consensus report on obesity-related kidney disease: proposal for a new classification.
AuthorsRico-Fontalvo J, Ciudin A, Correa-Rotter R, Díaz-Crespo FJ, Bonanno C, Lecube A, Daza-Arnedo R, Morales E, Quiroga B, Lorca E, Porrini E, Machado M, Polo VS, Álvarez G, Toniolo F, Soler MJ.
Year2025
JournalKidney International Kidney Int. 2025 Jul 3:S0085-2538(25)00505-8.
DOI10.1016/j.kint.2025.06.013
TitleInternational consensus on post-transplantation diabetes mellitus.
AuthorsSharif A, Chakkera H, de Vries APJ, Eller K, Guthoff M, Haller MC, Hornum M, Nordheim E, Kautzky-Willer A, Krebs M, Kukla A, Kurnikowski A, Schwaiger E, Montero N, Pascual J, Jenssen TG, Porrini E, Hecking M.
Year2024
JournalNephrology Dialysis Transplantation Nephrol Dial Transplant. 2024 Feb 28;39(3):531-549.
DOI10.1093/ndt/gfad258
TitlePost-Transplant Diabetes Mellitus and Prediabetes in Renal Transplant Recipients: An Update
AuthorsRodríguez-Rodríguez AE, Porrini E, Hornum M, Donate-Correa J, Morales-Febles R, Khemlani Ramchand S, Molina Lima MX, Torres A
Year2021
JournalNephron Nephron. 2021;145(4):317-329
DOI10.1159/000514288
TitleBeta-Cell Dysfunction Induced by Tacrolimus: A Way to Explain Type 2 Diabetes?
AuthorsRodriguez-Rodriguez AE, Porrini E, Torres A
Year2021
JournalInternational Journal of Molecular Sciences Int J Mol Sci. 2021 Sep 24;22(19):10311
DOI10.3390/ijms221910311
TitleReply to “Strengths and limitations of estimated and measured GFR”
AuthorsPorrini E, Ruggenenti P, Luis-Lima S, Carrara F, Jiménez A, de Vries APJ, Torres A, Gaspari F, Remuzzi G
Year2019
JournalNature Reviews Nephrology Nat Rev Nephrol 15, 785?786 (2019)
DOI10.1038/s41581-019-0214-8
TitleSGLT-2 inhibitors and GLP-1 receptor agonists for nephroprotection and cardioprotection in patients with diabetes mellitus and chronic kidney disease. A consensus statement by the EURECA-m and the DIABESITY working groups of the ERA-EDTA
AuthorsSarafidis P, Ferro CJ, Morales E, Ortiz A, Malyszko J, Hojs R, Khazim K, Ekart R, Valdivielso J, Fouque D, London GM, Massy Z, Ruggenenti P, Porrini E, Wiecek A, Zoccali C, Mallamaci F, Hornum M
Year2019
JournalNephrology Dialysis Transplantation Nephrol Dial Transplant. 2019 Feb 1;34(2):208-230
DOI10.1093/ndt/gfy407
TitleThe Modern Western Diet Rich in Advanced Glycation End-Products (AGEs): An Overview of Its Impact on Obesity and Early Progression of Renal Pathology
AuthorsBettiga A, Fiorio F, Di Marco F, Trevisani F, Romani A, Porrini E, Salonia A, Montorsi F, Vago R
Year2019
JournalNutrients Nutrients. 2019 Jul 30;11(8). pii: E1748
DOI10.3390/nu11081748
TitleEstimated GFR: time for a critical appraisal
AuthorsPorrini E, Ruggenenti P, Luis-Lima S, Carrara F, Jiménez A, de Vries APJ, Torres A, Gaspari F, Remuzzi G
Year2018
JournalNature Reviews Nephrology 15, 177?190 (2019)
DOI10.1038/s41581-018-0080-9
TitleIohexol plasma clearance for measuring glomerular filtration rate in clinical practice and research: a review. Part 2: Why to measure glomerular filtration rate with iohexol?
AuthorsDelanaye P, Melsom T, Ebert N, Bäck SE, Mariat C, Cavalier E, Björk J, Christensson A, Nyman U, Porrini E, Remuzzi G, Ruggenenti P, Schaeffner E, Soveri I, Sterner G, Eriksen BO, Gaspari F
Year2016
JournalClinical Kidney Journal Clin Kidney J. 2016;9:700-4
DOI10.1093/ckj/sfw071
TitleObesity-related glomerulopathy: clinical and pathologic characteristics and pathogenesis
AuthorsD’Agati VD, Chagnac A, de Vries AP, Levi M, Porrini E, Herman-Edelstein M, Praga M
Year2016
JournalNature Reviews Nephrology Nat Rev Nephrol. 2016 Aug;12(8):453-71
DOI10.1038/nrneph.2016.75
TitleIohexol plasma clearance for measuring glomerular filtration rate in clinical practice and research: a review. Part 1: How to measure glomerular filtration rate with iohexol?
AuthorsDelanaye P, Ebert N, Melsom T, Gaspari F, Mariat C, Cavalier E, Björk J, Christensson A, Nyman U, Porrini E, Remuzzi G, Ruggenenti P, Schaeffner E, Soveri I, Sterner G, Eriksen BO, Bäck SE
Year2016
JournalClinical Kidney Journal Clin Kidney J. 2016 Oct;9(5):682-99
DOI10.1093/ckj/sfw070
TitleAn Overview of Errors and Flaws of Estimated GFR versus True GFR in Patients with Diabetes Mellitus
AuthorsLuis-Lima S, Porrini E
Year2016
JournalNephron 2017;136(4):287-291
DOI10.1159/000453531
TitleNon-Proteinuric Pathways in loss of Renal Function in patients with Type 2 diabetes?
AuthorsPorrini E, Ruggenenti P, Mogensen CE, Barlovic DP, Praga M, Cruzado JM, Hojs R, Abbate M, de Vries AP
Year2015
JournalThe Lancet Diabetes & Endocrinology 2015 May;3(5):382-91
DOI10.1016/S2213-8587(15)00094-7
TitleFatty kidney: emerging role of ectopic lipid in obesity-related renal disease
Authorsde Vries AP, Ruggenenti P, Ruan XZ, Praga M, Cruzado JM, Bajema IM, D’Agati VD, Lamb HJ, Pongrac Barlovic D, Hojs R, Abbate M, Rodriquez R, Mogensen CE, Porrini E
Year2014
JournalThe Lancet Diabetes & Endocrinology 2014 May;2(5):417-26
DOI10.1016/S2213-8587(14)70065-8
TitleMetabolic syndrome, insulin resistance, and chronic allograft dysfunction
AuthorsPorrini E, Delgado P, Torres A
Year2010
JournalKidney International Volume 78, S42 – S46
DOI10.1038/ki.2010.422
Last modified: 04/08/2025 by Equipo de Redacción