Welcome to the LFR website.
We are a research group located at the Faculty of Medicine of the University of La Laguna (Tenerife – Canary Islands) which daily work is devoted to the evaluation of renal function with a gold standard method: the clearance of iohexol.
In the last years the group developed and validated this method to measure glomerular filtration rate in clinical research and in day-to-day clinical practice, in patients in which a reliable method to evaluate renal function in necessary. More recently we simplified the method using the dried blood spot technique (DBS), which is a major step forward in order to disseminate the use of measured GFR in clinical practice. The DBS approach is simple, cheap, reduces to a minimum the blood needed for analysis and is safe. Also, we developed the clearance of iohexol in animal models, either small (mice-rats) or large (swine-sheep).
With the clearance of iohexol using DBS we have developed diverse lines of clinical and pre-clinical research in renal disease related to:
- obesity and metabolic syndrome
- renal and non-renal transplantation
- chronic kidney disease
- living donors, among others.
LFR works in collaboration with the Hospital Universitario de Canarias (Tenerife)